Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208919 | 0.84 | MAP4K1 (0.36) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL21482756 | 0.83 | MAP4K1 (0.41) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL29624927 | 0.83 | MAP4K1 (0.41) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL21486348 | 0.78 | MAP4K1 (0.42) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL20209076 | 0.74 | MAPK1 (0.37) | — | |
| SCHEMBL17090692 | 0.70 | ADORA2A (0.38) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL13072745 | 0.68 | ADORA2A (0.37) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL20780955 | 0.66 | GRM5 (0.46) | — | |
| SCHEMBL5925821 | 0.65 | ADORA2A (0.35) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL20780881 | 0.60 | GRM5 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096325-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | Enterprise Therapeutics Limited (GB) | 2018-05-31 | — | — | WO | disclosed |