Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 13/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20209601 | 1.00 | ACSS2 (0.50) | ACSS2HTTBRD4PTGER4HDAC6 | |
| SCHEMBL2022140 | 0.91 | HDAC6 (0.52) | HTTBRD4PTGER4HDAC6 | |
| SCHEMBL20209579 | 0.91 | ACSS2 (0.47) | ACSS2HTTBRD4 | |
| SCHEMBL12635683 | 0.90 | ACSS2 (0.53) | ACSS2HTTBRD4 | |
| SCHEMBL12635694 | 0.87 | HTT (0.52) | ACSS2HTTBRD4 | |
| SCHEMBL12636253 | 0.87 | ACSS2 (0.47) | ACSS2HTTBRD4 | |
| SCHEMBL20209591 | 0.86 | BRD4 (0.49) | ACSS2HTTBRD4 | |
| SCHEMBL12635703 | 0.86 | BRD4 (0.49) | ACSS2HTTBRD4 | |
| SCHEMBL12634807 | 0.86 | ACSS2 (0.46) | ACSS2HTTBRD4HDAC6 | |
| SCHEMBL20935024 | 0.85 | ACSS2 (0.46) | ACSS2HTTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214141-B | Benzodiazolium compounds as ENaC inhibitors | 企业治疗学有限公司 | 2022-05-31 | — | — | CN | disclosed |