Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21836896 | 1.00 | TTR (0.45) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL29625010 | 0.85 | PTPRC (0.42) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL15492061 | 0.82 | TTR (0.47) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL8080620 | 0.81 | ACE2 (0.56) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL27825583 | 0.79 | ACE2 (0.46) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL29171910 | 0.79 | ACE2 (0.46) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL30848060 | 0.79 | ACE2 (0.46) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL25949222 | 0.79 | NOTUM (0.58) | TDP1MEN1KMT2ATSHRTP53 | |
| SCHEMBL18285572 | 0.78 | LMNA (0.50) | TTRGRM1TDP1MEN1CYP1A2 | |
| SCHEMBL30211952 | 0.78 | ACE2 (0.49) | TTRGRM1TDP1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003309-B | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4244213-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| CN-116745288-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116003309-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022103899-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022053010-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-03-17 | — | — | WO | disclosed |