SCHEMBL29625167

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	12/20	0.49

▸	NPY1R	P25929	7/20	0.49

▸	NPY2R	P49146	5/20	0.49

▸	NPY5R	Q15761	5/20	0.49

▸	BACE1	P56817	7/20	0.46

▸	TFPI	P10646	1/20	0.45

▸	CTSD	P07339	2/20	0.44

▸	BACE2	Q9Y5Z0	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29696019	0.98	NPY4R (0.49)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL30692435	0.94	TFPI (0.47)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29837350	0.92	TFPI (0.47)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL30381394	0.92	TASP1 (0.49)	NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL30768183	0.92	BACE1 (0.53)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29837349	0.91	TFPI (0.46)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29630327	0.91	NPY4R (0.57)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL31514374	0.91	NPY4R (0.57)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL31462927	0.91	TFPI (0.48)	NPY4RNPY1RNPY2RNPY5RTFPI
SCHEMBL31688310	0.90	TFPI (0.57)	BACE1TFPICTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4003533-A1	METHODS OF TREATING MULTIFOCAL CANCER	Nymox Corporation (US)	2022-06-01	—	—	EP	disclosed
EP-4003387-A1	FOCAL TREATMENT OF PROSTATE CANCER	Nymox Corporation (US)	2022-06-01	—	—	EP	disclosed