SCHEMBL29625516

SCHEMBL29625516

NC1CCCN(C2CC(c3ccc(F)cc3)CC2Oc2cncnc2)C1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TRPC3 Q13507 20/20 0.75
▸ TRPC6 Q9Y210 19/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21550554 0.85 TRPC3 (1.00) TRPC3TRPC6
SCHEMBL23068179 0.85 TRPC3 (1.00) TRPC3TRPC6
SCHEMBL30367180 0.84 TRPC3 (0.71) TRPC3TRPC6
SCHEMBL21550639 0.84 TRPC3 (1.00) TRPC3TRPC6
SCHEMBL21563724 0.84 TRPC3 (1.00) TRPC3TRPC6
SCHEMBL30366974 0.83 TRPC3 (0.77) TRPC3TRPC6
SCHEMBL21550297 0.83 TRPC3 (1.00) TRPC3TRPC6
SCHEMBL23068130 0.83 TRPC3 (1.00) TRPC3TRPC6
SCHEMBL23082672 0.83 TRPC3 (0.82) TRPC3TRPC6
SCHEMBL21550530 0.83 TRPC3 (1.00) TRPC3TRPC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220194922-A1 CYCLOPENTANE COMPOUNDS DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2022-06-23 — — US claimed
EP-3790870-B1 CYCLOPENTANE COMPOUNDS DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2023-04-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194922-A1 CYCLOPENTANE COMPOUNDS CYP11B2, CYP11B1, SQLE TRPC3 3056/4885TRPC6 3706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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