Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29063200 | 1.00 | KDM4E (0.31) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL17355420 | 0.85 | CTSL (0.33) | — | |
| SCHEMBL29063204 | 0.81 | — | — | |
| SCHEMBL29625873 | 0.81 | — | — | |
| SCHEMBL29625860 | 0.81 | — | — | |
| SCHEMBL17369392 | 0.81 | CTSL (0.40) | — | |
| SCHEMBL17355448 | 0.81 | AR (0.31) | — | |
| SCHEMBL17355475 | 0.79 | HTR2A (0.30) | — | |
| SCHEMBL17355527 | 0.79 | HTR2A (0.30) | — | |
| SCHEMBL17377903 | 0.78 | CTSL (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263749-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | Merck Patent GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| CN-116670255-A | Dibenzofuran and dibenzothiophene derivatives | 默克专利股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022128847-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |