Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474262 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HIF1AF2RL3HTTTDP1 | |
| SCHEMBL29589469 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HIF1AF2RL3HTTTDP1 | |
| SCHEMBL21962253 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HIF1AF2RL3HTTTDP1 | |
| SCHEMBL28462063 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HIF1AHTTTDP1GAA | |
| SCHEMBL3647032 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HIF1AHTTTDP1GAA | |
| SCHEMBL5839343 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HIF1AHTTTDP1GAA | |
| SCHEMBL13229385 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HIF1AHTTTDP1GAA | |
| SCHEMBL12955135 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HIF1AHTTTDP1GAA | |
| SCHEMBL4645930 | 0.81 | MEN1 (0.48) | ALDH1A1HIF1AHTTGAATHRB | |
| SCHEMBL11317000 | 0.81 | HTT (0.49) | ALDH1A1F2RL3HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423743-A | Triazine derivatives for the treatment of diseases associated with neurotrophic factors | 阿泽克制药公司 | 2022-04-29 | — | — | CN | disclosed |