Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629404 | 1.00 | HDAC6 (0.65) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL2224875 | 0.87 | HDAC6 (0.59) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL16652875 | 0.85 | NPC1 (0.55) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL19071237 | 0.84 | HDAC6 (0.72) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL18824382 | 0.83 | HDAC6 (0.59) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL28499323 | 0.83 | HDAC6 (0.51) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL21806679 | 0.81 | HDAC6 (0.58) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL29757333 | 0.80 | HDAC4 (0.53) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL2225015 | 0.80 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL19745693 | 0.79 | HDAC6 (1.00) | HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112004813-B | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-116283955-B | Compound for targeted degradation of HDAC7, and preparation method and application thereof | 浙江大学 | 2025-06-17 | — | — | CN | disclosed |
| US-20240246956-A1 | CLASS IIA HISTONE DEACETYLASE (HDAC) DEGRADER LIGANDS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-07-25 | — | — | US | disclosed |
| CN-112004813-B | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-4333842-A1 | CLASS IIA HISTONE DEACETYLASE (HDAC) DEGRADER LIGANDS AND METHODS OF USE THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| CN-116283955-A | Compound for targeted degradation of HDAC7, and preparation method and application thereof | 浙江大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116253730-A | PROTAC compound for targeted degradation of HDAC7 protein and preparation method and application thereof | 浙江大学 | 2023-06-13 | — | — | CN | disclosed |
| WO-2022235565-A1 | CLASS IIA HISTONE DEACETYLASE (HDAC) DEGRADER LIGANDS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-20220169621-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246956-A1 | CLASS IIA HISTONE DEACETYLASE (HDAC) DEGRADER LIGANDS AND METHODS OF USE THEREOF | HDAC4, HDAC1, HDAC7 | HDAC6 9/4885HDAC1 2/4885HDAC8 6/4885 |
| US-20220169621-A1 | OXADIAZOLES FOR USE IN CONTROLLING PHYTOPATHOGENIC FUNGI | OXA1L, CYP51A1, CYP1A1 | HDAC6 1374/4885HDAC1 725/4885HDAC8 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.