SCHEMBL19071237

SCHEMBL19071237

NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 11/20 0.72
HDAC8 Q9BY41 4/20 0.72
HDAC1 Q13547 3/20 0.72
HDAC4 P56524 17/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21175499 0.89 HDAC4 (0.64) HDAC6HDAC8HDAC1HDAC4
SCHEMBL29757329 0.89 HDAC6 (0.60) HDAC6HDAC8HDAC1HDAC4
SCHEMBL27957379 0.89 HDAC4 (0.71) HDAC6HDAC8HDAC4
SCHEMBL14645472 0.87 HDAC4 (0.69) HDAC6HDAC8HDAC4
SCHEMBL29242114 0.87 HDAC4 (0.61) HDAC6HDAC8HDAC1HDAC4
SCHEMBL18824381 0.86 HDAC4 (0.66) HDAC6HDAC8HDAC1HDAC4
SCHEMBL18824437 0.86 HDAC4 (0.68) HDAC6HDAC8HDAC4
SCHEMBL19384968 0.86 HDAC4 (0.59) HDAC6HDAC8HDAC1HDAC4
SCHEMBL19100119 0.86 HDAC4 (0.72) HDAC6HDAC8HDAC1HDAC4
SCHEMBL18824435 0.85 HDAC4 (0.75) HDAC6HDAC1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118368985-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-19 CN claimed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN claimed
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN claimed
CN-115209736-A Fungicidal compositions 先正达农作物保护股份公司 2022-10-18 CN claimed
CN-114760842-A Active substance combinations comprising fatty acids 拜耳公司 2022-07-15 CN claimed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 CN claimed
CN-116283955-B Compound for targeted degradation of HDAC7, and preparation method and application thereof 浙江大学 2025-06-17 CN disclosed
CN-113661165-B Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2025-05-23 CN disclosed
CN-115210218-B Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2025-05-16 CN disclosed
CN-114630825-B Condensed with pesticidal activity bicyclic heteroaromatic compounds 先正达农作物保护股份公司 2025-05-16 CN disclosed
CN-116033828-B Heterocyclic derivatives as pest control agents 拜耳公司 2025-05-16 CN disclosed
CN-119998270-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2025-05-13 CN disclosed
CN-113597424-B Pesticidal active azole amide compounds 先正达农作物保护股份公司 2025-04-18 CN disclosed
US-20190161460-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-05-30 US disclosed
EP-3464251-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2019-04-10 EP disclosed
EP-3433252-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2019-01-30 EP disclosed
WO-2017207757-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-12-07 WO disclosed
WO-2017162868-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-09-28 WO disclosed
WO-2017162868-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-09-28 WO disclosed
EP-3187497-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2017-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190161460-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES PRF1, NOX1, ARG2 HDAC6 611/4885HDAC8 1774/4885HDAC1 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.