Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681514 | 1.00 | HCAR2 (0.55) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL29626505 | 0.93 | HCAR2 (0.57) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL347470 | 0.92 | PPARG (0.51) | MAPTLMNACNR1CNR2PPARG | |
| SCHEMBL14672999 | 0.92 | PPARG (0.51) | MAPTLMNACNR1CNR2PPARG | |
| SCHEMBL3710792 | 0.92 | PPARG (0.51) | MAPTLMNACNR1CNR2PPARG | |
| SCHEMBL25405291 | 0.92 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL22555479 | 0.92 | PPARG (0.51) | MAPTLMNACNR1CNR2PPARG | |
| SCHEMBL21952141 | 0.92 | MAPT (0.59) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL22555434 | 0.92 | PPARG (0.51) | MAPTLMNACNR1CNR2PPARG | |
| SCHEMBL11743976 | 0.92 | PPARG (0.51) | MAPTLMNACNR1CNR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-08-05 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | HCAR2 4210/4885KEAP1 394/4885NFE2L2 186/4885 |
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | HCAR2 4210/4885KEAP1 394/4885NFE2L2 186/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | HCAR2 4210/4885KEAP1 394/4885NFE2L2 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.