Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.44 |
| ▸ | MME | P08473 | 5/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626745 | 0.91 | MME (0.45) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL29630564 | 0.90 | SLC15A2 (0.43) | ACEMMECPA1ACE2 | |
| SCHEMBL29429284 | 0.88 | SLC15A2 (0.40) | ACEMMECPA1ACE2 | |
| SCHEMBL29590377 | 0.87 | SLC15A2 (0.40) | MME | |
| SCHEMBL29615620 | 0.86 | ACE (0.48) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL29894761 | 0.86 | OPRD1 (0.42) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL29531471 | 0.85 | ACE (0.47) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL5598789 | 0.84 | MME (0.46) | ACEMMECPA1ACE2 | |
| SCHEMBL5598794 | 0.84 | MME (0.46) | ACEMMECPA1ACE2 | |
| SCHEMBL30692732 | 0.84 | MME (0.46) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443096-B1 | COMPOSITIONS AND METHODS FOR SELECTIVE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS | NOVARTIS AG (CH) | 2023-03-01 | — | — | EP | claimed |
| EP-4004213-A1 | REGULATABLE EXPRESSION SYSTEMS | Novartis AG (CH) | 2022-06-01 | — | — | EP | claimed |