Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | KDM4B | O94953 | 2/20 | 0.45 |
| ▸ | KDM5C | P41229 | 2/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971254 | 1.00 | KDM4A (0.45) | KDM4AKDM4BKDM5CKDM5BKDM4C | |
| SCHEMBL20971053 | 0.85 | SRC (0.55) | LDHAALDH1A1SRCMAPTHTT | |
| SCHEMBL20971301 | 0.84 | KDM4A (0.45) | KDM4AKDM4BKDM5CKDM5BKDM4C | |
| SCHEMBL20971362 | 0.79 | PARP1 (0.42) | KDM4AKDM4BKDM5CKDM5BKDM4C | |
| SCHEMBL32668797 | 0.79 | HTT (0.51) | KDM4AKDM4BKDM5CKDM5BKDM4C | |
| SCHEMBL20971017 | 0.79 | MAPT (0.51) | ALDH1A1SRCMAPTPARP1HPGD | |
| SCHEMBL20971046 | 0.78 | LMNA (0.58) | ALDH1A1SRCMAPTHTTPARP1 | |
| SCHEMBL20971117 | 0.78 | KMT2A (0.50) | SRCMAPTPI4KAPI4K2BPI4K2A | |
| SCHEMBL17868975 | 0.78 | PIM1 (0.46) | ALDH1A1SRCMAPTPARP1PDPK1 | |
| SCHEMBL29627437 | 0.78 | PARP1 (0.46) | ALDH1A1SRCMAPTPARP1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | claimed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |