Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972006 | 0.84 | PBRM1 (0.33) | ALDH1A1 | |
| SCHEMBL2971813 | 0.82 | KDM1A (0.35) | CYP2A6ALDH1A1CYP1A2TSHRKDM1A | |
| SCHEMBL2960750 | 0.81 | KDM1A (0.39) | CYP2A6ALDH1A1CYP1A2TSHRKDM1A | |
| SCHEMBL2975815 | 0.80 | HTR2C (0.36) | — | |
| SCHEMBL2971968 | 0.80 | CYP2A6 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRKDM1A | |
| SCHEMBL2961427 | 0.80 | CYP2A6 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRKDM1A | |
| SCHEMBL2965048 | 0.80 | CYP2A6 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRKDM1A | |
| SCHEMBL2960040 | 0.80 | CYP2A6 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRKDM1A | |
| SCHEMBL2970149 | 0.78 | KIF11 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2959653 | 0.77 | EGFR (0.33) | CYP2A6ALDH1A1CYP1A2KDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | CYP2A6 2465/4885ALDH1A1 4332/4885CYP1A2 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.