Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303394 | 1.00 | ADRB3 (0.43) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL23111687 | 0.88 | RAF1 (0.47) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL30816945 | 0.88 | RAF1 (0.47) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL27314356 | 0.82 | GRM5 (0.37) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL2301174 | 0.82 | RECQL (0.39) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL15057624 | 0.81 | DYRK1A (0.48) | GRM5KCNH2MPISCN9ADYRK1A | |
| SCHEMBL1229896 | 0.80 | SCN5A (0.49) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL27314314 | 0.78 | GRM5 (0.37) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL30864848 | 0.78 | GRM5 (0.37) | ADRB3TSPOGRM5KCNH2TMEM97 | |
| SCHEMBL27160490 | 0.78 | KCNN3 (0.47) | RECQLLOXLOXL3LOXL2KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4687883-A2 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | Caraway Therapeutics, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| CN-119585250-A | KIT inhibitors | 蓝图药品公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024211249-A2 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2024-10-10 | — | — | WO | disclosed |
| CN-117425656-A | Purine derivatives as anticancer agents | 探戈医药股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| EP-3997096-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-05-18 | — | — | EP | disclosed |