Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 8/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29628831 | 0.99 | PTGS1 (0.43) | PTGS1GSTK1ACEMMECPA1 | |
| SCHEMBL29628816 | 0.88 | ACE (0.46) | PTGS1GSTK1ACEMMECPA1 | |
| SCHEMBL30835497 | 0.87 | QRFPR (0.41) | ACEMMECPA1ACE2OPRD1 | |
| SCHEMBL29865388 | 0.87 | ACE (0.46) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL19033088 | 0.85 | PTGS1 (0.40) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29567393 | 0.84 | PTGS1 (0.51) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29567345 | 0.84 | PTGS1 (0.51) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL30595915 | 0.84 | MME (0.39) | ACEMMECPA1ACE2KDM4E | |
| SCHEMBL6447460 | 0.84 | KDM4E (0.47) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL6447452 | 0.84 | KDM4E (0.47) | PTGS1GSTK1ACEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667113-B | Cysteine-linked nanobody dimers engineered through the C-terminus | 埃博灵克斯股份有限公司 | 2022-05-03 | — | — | CN | disclosed |