Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 10/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29628831 | 0.90 | PTGS1 (0.43) | ACEMMECPA1ACE2SMN1; SMN2 | |
| SCHEMBL29628817 | 0.88 | PTGS1 (0.42) | ACEMMECPA1ACE2SMN1; SMN2 | |
| SCHEMBL29351196 | 0.85 | MME (0.41) | ACEMMECPA1ACE2SMN1; SMN2 | |
| SCHEMBL30676225 | 0.85 | MME (0.41) | ACEMMECPA1ACE2SMN1; SMN2 | |
| SCHEMBL929660 | 0.84 | ACE (0.55) | ACEMMESMN1; SMN2KDM4EMAPT | |
| SCHEMBL31571457 | 0.83 | LTA4H (0.43) | ACEMMECPA1ACE2SMN1; SMN2 | |
| SCHEMBL29421960 | 0.83 | ALDH1A1 (0.44) | ACEMMECPA1ACE2MAPT | |
| SCHEMBL30905095 | 0.82 | GNPAT (0.44) | ACEMMECPA1ACE2LTA4H | |
| SCHEMBL7588867 | 0.81 | PTGS1 (0.42) | ACESMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL7588872 | 0.81 | PTGS1 (0.42) | ACESMN1; SMN2KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667113-B | Cysteine-linked nanobody dimers engineered through the C-terminus | 埃博灵克斯股份有限公司 | 2022-05-03 | — | — | CN | disclosed |