SCHEMBL29628903

SCHEMBL29628903

c1cc(-c2cccc3ccccc23)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.53
ACMSD Q8TDX5 1/20 0.53
CA12 O43570 2/20 0.51
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA9 Q16790 2/20 0.51
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 4/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 3/20 0.48
TSHR P16473 3/20 0.48
MAPT P10636 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
TP53 P04637 1/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
ATM Q13315 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14036308 1.00 MCL1 (0.53) MCL1ACMSDCA12CA1CA2
SCHEMBL16796022 0.95 MCL1 (0.50) MCL1ACMSDCA12CA1CA2
SCHEMBL24816033 0.93 CA12 (0.56) MCL1ACMSDCA12CA1CA2
SCHEMBL29628965 0.93 CA12 (0.56) MCL1ACMSDCA12CA1CA2
SCHEMBL29892508 0.93 CA12 (0.56) MCL1ACMSDCA12CA1CA2
SCHEMBL29866205 0.92 CA12 (0.50) MCL1ACMSDCA12CA1CA2
SCHEMBL2010178 0.92 CA12 (0.50) MCL1ACMSDCA12CA1CA2
SCHEMBL316112 0.90 TNF (0.57) MCL1ACMSDCA12CA1CA2
SCHEMBL27655623 0.89 ALDH1A1 (0.46) MCL1ACMSDCA12CA1CA2
SCHEMBL23633535 0.89 KDM4E (0.50) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621045-A Method for synthesizing polyaromatic hydrocarbon from aryl formaldehyde 长沙资材科技有限公司 2022-06-14 CN disclosed