Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.78 |
| ▸ | ABL1 | P00519 | 15/20 | 0.72 |
| ▸ | BCR | P11274 | 13/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.72 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.72 |
| ▸ | EGFR | P00533 | 2/20 | 0.70 |
| ▸ | JAK3 | P52333 | 1/20 | 0.70 |
| ▸ | BTK | Q06187 | 1/20 | 0.70 |
| ▸ | ITK | Q08881 | 1/20 | 0.70 |
| ▸ | KIT | P10721 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349322 | 1.00 | PRKCA (0.78) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL15159937 | 0.88 | PRKCA (1.00) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL18814452 | 0.87 | PRKCA (0.81) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL23246300 | 0.85 | ABL1 (0.86) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL22793720 | 0.85 | PRKCA (0.78) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL1566169 | 0.84 | ABL1 (0.72) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL12320924 | 0.84 | ABL1 (0.78) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL19556857 | 0.84 | ABL1 (1.00) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL2229310 | 0.83 | EGFR (1.00) | PRKCAABL1BCRPDGFRAPDGFRB | |
| SCHEMBL28434538 | 0.82 | PRKCA (0.53) | PRKCAABL1BCRPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656451-A | Benzamide derivative, preparation method and application | 海南医学院 | 2022-06-24 | — | — | CN | claimed |
| CN-114656451-A | Benzamide derivative, preparation method and application | 海南医学院 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656451-A | Benzamide derivative, preparation method and application | 海南医学院 | 2022-06-24 | — | — | CN | disclosed |