Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27683141 | 0.96 | ALOX5 (0.61) | ALOX5HTR6PARP15PARP10SIGMAR1 | |
| SCHEMBL10242486 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL27945144 | 0.89 | ALOX5 (0.56) | ALOX5HTR6PTGIRTDP1DAO | |
| SCHEMBL18787484 | 0.80 | ALOX5 (0.47) | ALOX5SIGMAR1PTGIR | |
| SCHEMBL21058086 | 0.78 | ALOX5 (0.45) | ALOX5SIGMAR1PTGIRBACE1 | |
| SCHEMBL24630130 | 0.77 | ALOX5 (0.38) | ALOX5TDP1 | |
| SCHEMBL9308267 | 0.76 | ALOX5 (1.00) | ALOX5PARP15PARP10PARP2TDP1 | |
| SCHEMBL20251406 | 0.75 | ALOX5 (0.42) | ALOX5PTGIR | |
| SCHEMBL25692128 | 0.75 | ALOX5 (0.42) | ALOX5PTGIR | |
| SCHEMBL3373961 | 0.74 | ALOX5 (0.48) | ALOX5SIGMAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621135-B | LPA1 small molecule antagonist | 上海拓界生物医药科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114621135-A | LPA1 small molecule antagonist | 上海拓界生物医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |