Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410730 | 1.00 | HTR2A (0.54) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL29666655 | 0.87 | HTR2A (0.46) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL13736848 | 0.85 | HTR2A (0.55) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL23056443 | 0.84 | HTR2A (0.54) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL6646865 | 0.84 | HTR2A (0.54) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL9140032 | 0.84 | HTR2A (0.57) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL29629122 | 0.83 | HTR2A (0.50) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL6394617 | 0.82 | HTR2A (0.52) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL29586770 | 0.82 | ALDH1A1 (0.57) | HTR2AALDH1A1KMT2ABCL9CTNNB1 | |
| SCHEMBL25171178 | 0.82 | HTR2A (0.52) | HTR2AALDH1A1KMT2ABCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621135-A | LPA1 small molecule antagonist | 上海拓界生物医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |