Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 4/20 | 1.00 |
| ▸ | USP19 | O94966 | 2/20 | 1.00 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 1.00 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.77 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | USP8 | P40818 | 2/20 | 0.73 |
| ▸ | OTUB1 | Q96FW1 | 2/20 | 0.73 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.73 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808226 | 1.00 | USP1 (1.00) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL29629184 | 1.00 | USP1 (1.00) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL19220486 | 0.90 | USP1 (0.82) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL18347790 | 0.88 | USP1 (0.79) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL18203587 | 0.88 | USP1 (0.79) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL7968066 | 0.87 | USP1 (0.77) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL7815859 | 0.87 | USP1 (1.00) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL7808410 | 0.87 | USP1 (0.77) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL31276578 | 0.87 | USP1 (1.00) | USP1USP19WDR48UCHL3USP2 | |
| SCHEMBL19225117 | 0.87 | USP1 (0.77) | USP1USP19WDR48UCHL3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118903428-B | Application of USP1 inhibitor in preparation of medicine for enhancing STING-mediated antitumor immunity | 暨南大学附属第一医院（广州华侨医院） | 2025-05-30 | — | — | CN | claimed |
| CN-118903428-B | Application of USP1 inhibitor in preparation of medicine for enhancing STING-mediated antitumor immunity | 暨南大学附属第一医院（广州华侨医院） | 2025-05-30 | — | — | CN | disclosed |
| CN-118903428-A | Application of USP1 inhibitor in preparation of medicine for enhancing STING-mediated antitumor immunity | 暨南大学附属第一医院（广州华侨医院） | 2024-11-08 | — | — | CN | disclosed |
| CN-114617879-A | Application of SJB2-043 as drug for inhibiting glioblastoma | 中国人民解放军陆军军医大学第一附属医院 | 2022-06-14 | — | — | CN | disclosed |