Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.63 |
| ▸ | HTR5A | P47898 | 1/20 | 0.63 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD5 | P21918 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561615 | 1.00 | HTR2A (0.71) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL30160092 | 0.87 | KDM4E (0.73) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL104598 | 0.87 | KDM4E (0.73) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL481360 | 0.87 | KDM4E (0.68) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL29936982 | 0.87 | KDM4E (0.68) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL14156164 | 0.85 | SMN1; SMN2 (0.74) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL11641810 | 0.85 | SMN1; SMN2 (0.74) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL15266076 | 0.85 | KDM4E (0.71) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| SCHEMBL7402531 | 0.85 | KDM4E (0.71) | HTR2AHTR2CKDM4ENR2E1HTR5A | |
| Bromide SCHEMBL8568783 | 0.85 | KDM4E (0.71) | HTR2AHTR2CKDM4ENR2E1HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072481-B | Indolo-cyclobutane skeleton compound, synthesis method and application | 五邑大学 | 2022-06-24 | — | — | CN | claimed |
| CN-113072481-B | Indolo-cyclobutane skeleton compound, synthesis method and application | 五邑大学 | 2022-06-24 | — | — | CN | disclosed |