Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470866 | 1.00 | KMT2A (0.60) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL24471133 | 0.87 | CYP3A4 (0.61) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL29630200 | 0.87 | CYP3A4 (0.61) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL24484510 | 0.84 | MEN1 (0.59) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL29630277 | 0.84 | MEN1 (0.59) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL24470719 | 0.81 | GAA (0.55) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL29713119 | 0.81 | GAA (0.55) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL16453510 | 0.78 | MAPT (0.69) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL24470869 | 0.78 | L3MBTL1 (0.56) | KMT2AMAPTCYP3A4MEN1CYP1A2 | |
| SCHEMBL30569391 | 0.78 | L3MBTL1 (0.56) | KMT2AMAPTCYP3A4MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259613-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |