Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096040 | 1.00 | SLC26A4 (0.51) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL29630173 | 0.88 | MAPT (0.49) | SLC26A4KMT2AMEN1POLBLMNA | |
| SCHEMBL29095839 | 0.88 | MAPT (0.49) | SLC26A4KMT2AMEN1POLBLMNA | |
| SCHEMBL24485031 | 0.87 | SLC26A4 (0.69) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL29095857 | 0.85 | SLC26A4 (0.49) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL29630302 | 0.85 | SLC26A4 (0.49) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL29630228 | 0.84 | SLC26A4 (0.53) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL24484889 | 0.84 | SLC26A4 (0.53) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL24484891 | 0.84 | SLC26A4 (0.48) | SLC26A4KMT2AMEN1ANO1POLB | |
| SCHEMBL29629767 | 0.84 | SLC26A4 (0.48) | SLC26A4KMT2AMEN1ANO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |