SCHEMBL29630347

SCHEMBL29630347

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nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.46
RIMKLA Q8IXN7 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.46
BACE1 P56817 5/20 0.43
CTSD P07339 2/20 0.43
ECE1 P42892 2/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
GNPAT O15228 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517720 0.96 GNPAT (0.43) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL29517500 0.95 GNPAT (0.44) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL30390544 0.93 FOLH1 (0.44) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL30663332 0.91 FOLH1 (0.55) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL29530951 0.91 FOLH1 (0.55) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL31182862 0.90 BACE1 (0.45) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL29888969 0.90 FOLH1 (0.50) FOLH1RIMKLANAALAD2BACE1CTSD
SCHEMBL30010888 0.90 TGFBR1 (0.47) BACE1CTSDECE1PDCD1LG2CD274
SCHEMBL29630431 0.89 TGFBR1 (0.41) BACE1CTSDECE1PDCD1LG2CD274
SCHEMBL31410836 0.89 FOLH1 (0.49) FOLH1RIMKLANAALAD2BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed