Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.57 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802215 | 1.00 | BACE1 (0.57) | BACE1BACE2NAALAD2MMECTSD | |
| SCHEMBL29469738 | 0.96 | NAALAD2 (0.61) | BACE1BACE2NAALAD2MMECTSD | |
| SCHEMBL29630590 | 0.94 | BACE1 (0.54) | BACE1BACE2NAALAD2MMECTSD | |
| SCHEMBL8821940 | 0.94 | NAALAD2 (0.64) | BACE1BACE2NAALAD2MMECTSD | |
| SCHEMBL29592259 | 0.93 | BACE1 (0.61) | BACE1BACE2NAALAD2CTSDMMP1 | |
| SCHEMBL29892410 | 0.92 | NAALAD2 (0.67) | BACE1BACE2NAALAD2CTSDGNPAT | |
| SCHEMBL29630435 | 0.91 | MME (0.60) | BACE1NAALAD2MMEGNPATENPEP | |
| SCHEMBL29430082 | 0.91 | MME (0.60) | NAALAD2MMEGNPATENPEPLTA4H | |
| SCHEMBL2980529 | 0.91 | NAALAD2 (0.68) | BACE1BACE2NAALAD2MME | |
| SCHEMBL3748615 | 0.91 | NAALAD2 (0.68) | BACE1BACE2NAALAD2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |