SCHEMBL2980529

SCHEMBL2980529

N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NAALAD2 Q9Y3Q0 3/20 0.68
MME P08473 3/20 0.58
BACE1 P56817 4/20 0.56
SLC15A1 P46059 1/20 0.55
BACE2 Q9Y5Z0 1/20 0.54
ACE P12821 2/20 0.53
CPA1 P15085 2/20 0.53
ACE2 Q9BYF1 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3748615 1.00 NAALAD2 (0.68) NAALAD2MMEBACE1SLC15A1BACE2
SCHEMBL29602993 1.00 NAALAD2 (0.68) NAALAD2MMEBACE1SLC15A1BACE2
SCHEMBL3732243 1.00 NAALAD2 (0.68) NAALAD2MMEBACE1SLC15A1BACE2
SCHEMBL27914476 1.00 NAALAD2 (0.68) NAALAD2MMEBACE1SLC15A1BACE2
SCHEMBL8821940 0.97 NAALAD2 (0.64) NAALAD2MMEBACE1SLC15A1BACE2
SCHEMBL29827935 0.96 NAALAD2 (0.67) NAALAD2MMEBACE1BACE2
SCHEMBL29469738 0.95 NAALAD2 (0.61) NAALAD2MMEBACE1BACE2
SCHEMBL29603574 0.94 NAALAD2 (0.60) NAALAD2MMEBACE1BACE2
Trifluoroacetic Acid SCHEMBL29617362 0.94 NAALAD2 (0.60) NAALAD2MMEBACE1SLC15A1BACE2
SCHEMBL29531169 0.94 NAALAD2 (0.60) NAALAD2MMEBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014232-A1 Pharmaceutical Composition of GLP-1 and GIP Receptor Dual Agonist and Use Thereof JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) 2026-01-15 US claimed
EP-4659591-A1 TASTE-ENHANCING COMPOSITION, METHOD FOR PRODUCING SAME, FOOD PRODUCT, AND METHOD FOR ENHANCING TASTE OF FOOD PRODUCT House Foods Group Inc. (JP) 2025-12-10 EP claimed
EP-4659592-A1 FLAVOR ENHANCING COMPOSITION, MANUFACTURING METHOD THEREFOR, AND METHOD FOR ENHANCING FLAVOR OF FOOD PRODUCT House Foods Corporation (JP) 2025-12-10 EP claimed
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 US claimed
WO-2025093774-A1 GLUCAGON-LIKE PEPTIDE 1 AGONISTS Constructive Biology Limited (GB) 2025-05-08 WO claimed
US-20250115654-A1 PHARMACEUTICAL COMPOSITION OF GLP-1 RECEPTOR AND GIP RECEPTOR DUAL AGONIST, AND USE THEREOF Fujian Shengdi Pharmaceutical Co., Ltd. (CN) 2025-04-10 US claimed
CN-119780446-A Biomarker for milk cow early pregnancy related state and application thereof 宁夏大学 2025-04-08 CN claimed
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 CN claimed
CN-118897023-A Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2024-11-05 CN claimed
CN-118754965-A GLP-1 and GIP receptor dual agonist compounds and uses thereof 北京拓界生物医药科技有限公司 2024-10-11 CN claimed
EP-2546649-B1 Biomarkers for fatty liver disease and methods using the same METABOLON INC (US) 2015-02-25 EP claimed
EP-2546649-A2 Biomarkers for fatty liver disease and methods using the same Metabolon Inc. (US) 2013-01-16 EP claimed
EP-2227689-B1 BIOMARKERS FOR FATTY LIVER DISEASE AND METHODS USING THE SAME METABOLON INC (US) 2012-12-26 EP claimed
US-20100279956-A1 Biomarkers For Fatty Liver Disease And Methods Using The Same METABOLON, INC. 2010-11-04 US claimed
US-5643955-A CARBOXYL-CONTAINING DIPEPTIDES AND DERIVATIVES (TASTANDS) TO REDUCE OR ELIMIATE A ITTER OR METALLIC TASTE; FOODS; DRUGS; ARTIFICIAL SWEETENERS; POTASSIUM CHLORIDE BIORESEARCH, INC. (US) 1997-07-01 US claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
EP-0728419-A2 Ingestible containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers BIORESEARCH, INC. (US) 1996-08-28 EP claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12377110-B2 Fospropofol methods and compositions FOS, FOSB, PFAS NAALAD2 4066/4885MME 2240/4885BACE1 72/4885
US-20260014232-A1 Pharmaceutical Composition of GLP-1 and GIP Receptor Dual Agonist and Use Thereof GLP1R, GIPR, GCGR NAALAD2 1969/4885MME 3730/4885BACE1 1593/4885
US-20250115654-A1 PHARMACEUTICAL COMPOSITION OF GLP-1 RECEPTOR AND GIP RECEPTOR DUAL AGONIST, AND USE THEREOF GLP1R, GIPR, GCGR NAALAD2 2901/4885MME 1798/4885BACE1 3735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.