Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 6/20 | 0.53 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630658 | 0.94 | BACE1 (0.56) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL30900768 | 0.92 | OPRD1 (0.54) | NPY1RNPY2RNPY4ROPRD1OPRM1 | |
| SCHEMBL29416799 | 0.90 | BACE1 (0.58) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL30343582 | 0.90 | NPY4R (0.55) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL29767368 | 0.90 | NPY4R (0.55) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL29591878 | 0.89 | NAALAD2 (0.61) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL29608986 | 0.89 | NPY4R (0.57) | NPY1RNPY2RNPY4RBACE1NAALAD2 | |
| SCHEMBL30799896 | 0.88 | BACE1 (0.66) | BACE1BACE2NAALAD2CTSD | |
| SCHEMBL2184740 | 0.88 | NPY4R (0.66) | NPY1RNPY2RNPY4RBACE1BACE2 | |
| SCHEMBL30799648 | 0.88 | BACE1 (0.62) | BACE1BACE2OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |