SCHEMBL29630484

SCHEMBL29630484

NC(=O)CC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
DPP7 Q9UHL4 1/20 0.40
CTSC P53634 3/20 0.37
CTSD P07339 1/20 0.37
BACE1 P56817 1/20 0.37
REN P00797 1/20 0.35
BMP1 P13497 1/20 0.34
ECE1 P42892 1/20 0.34
MAPK8 P45983 1/20 0.34
MAPK9 P45984 1/20 0.34
MAPK10 P53779 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630350 0.97 MEN1 (0.41) KMT2AMEN1DPP7CTSCCTSD
SCHEMBL30910373 0.95 KMT2A (0.46) KMT2AMEN1DPP7CTSC
SCHEMBL29630487 0.95 KMT2A (0.46) KMT2AMEN1DPP7CTSC
SCHEMBL29608142 0.94 MEN1 (0.44) KMT2AMEN1DPP7CTSCCTSD
SCHEMBL30193330 0.91 MEN1 (0.41) KMT2AMEN1DPP7CTSCREN
SCHEMBL30582932 0.91 BACE1 (0.41) KMT2AMEN1DPP7CTSDBACE1
SCHEMBL5970814 0.91 KMT2A (0.49) KMT2AMEN1DPP7CTSC
SCHEMBL21647349 0.91 KMT2A (0.49) KMT2AMEN1DPP7CTSC
SCHEMBL5970810 0.91 KMT2A (0.49) KMT2AMEN1DPP7CTSC
SCHEMBL29376508 0.88 MEN1 (0.47) KMT2AMEN1DPP7CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed