SCHEMBL29608142

SCHEMBL29608142

NC(=O)CC[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
DPP7 Q9UHL4 1/20 0.40
FOLH1 Q04609 3/20 0.39
NAALAD2 Q9Y3Q0 2/20 0.39
RIMKLA Q8IXN7 1/20 0.39
CTSC P53634 1/20 0.38
BMP1 P13497 1/20 0.37
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
EPHX2 P34913 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30910373 0.96 KMT2A (0.46) MEN1KMT2ADPP7CTSC
SCHEMBL29630487 0.96 KMT2A (0.46) MEN1KMT2ADPP7CTSC
SCHEMBL29630484 0.94 KMT2A (0.43) MEN1KMT2ADPP7CTSCBMP1
SCHEMBL29376508 0.94 MEN1 (0.47) MEN1KMT2ADPP7FOLH1NAALAD2
SCHEMBL29413008 0.93 FOLH1 (0.49) MEN1KMT2ADPP7FOLH1
SCHEMBL30193330 0.92 MEN1 (0.41) MEN1KMT2ADPP7CTSCBMP1
SCHEMBL5970814 0.92 KMT2A (0.49) MEN1KMT2ADPP7CTSC
SCHEMBL5970810 0.92 KMT2A (0.49) MEN1KMT2ADPP7CTSC
SCHEMBL21647349 0.92 KMT2A (0.49) MEN1KMT2ADPP7CTSC
SCHEMBL29630350 0.91 MEN1 (0.41) MEN1KMT2ADPP7CTSCBMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367169-A1 FORMULATIONS FOR PERSONALIZED METHODS OF TREATMENT FAETH THERAPEUTICS INC (US) 2025-12-04 US disclosed
US-12220402-B2 Formulations for personalized methods of treatment FAETH THERAPEUTICS, INC. (US) 2025-02-11 US disclosed
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-11-07 US disclosed
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds SEAGEN INC. (US) 2024-07-16 US disclosed
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-06-27 US disclosed
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC. 2023-03-23 US disclosed
US-20220117943-A1 FORMULATIONS FOR PERSONALIZED METHODS OF TREATMENT FAETH THERAPEUTICS, INC. 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ MEN1 1450/4885KMT2A 3707/4885DPP7 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.