Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590787 | 0.99 | BACE1 (0.60) | BACE1CTSDNAALAD2GNPATBACE2 | |
| SCHEMBL30460370 | 0.97 | BACE1 (0.60) | BACE1CTSDNAALAD2BACE2 | |
| SCHEMBL29725302 | 0.93 | BACE1 (0.54) | BACE1CTSDGNPATMME | |
| SCHEMBL29630600 | 0.93 | BACE1 (0.55) | BACE1CTSDNAALAD2GNPATBACE2 | |
| SCHEMBL31094953 | 0.93 | NAALAD2 (0.60) | BACE1CTSDNAALAD2GNPATBACE2 | |
| SCHEMBL30903437 | 0.92 | BACE1 (0.51) | BACE1CTSDNAALAD2GNPATMME | |
| SCHEMBL29695561 | 0.92 | BACE1 (0.65) | BACE1CTSDNAALAD2BACE2 | |
| SCHEMBL29592259 | 0.92 | BACE1 (0.61) | BACE1CTSDNAALAD2BACE2 | |
| SCHEMBL31482978 | 0.92 | BACE1 (0.52) | BACE1CTSDNAALAD2GNPATMME | |
| SCHEMBL29630438 | 0.92 | BACE1 (0.52) | BACE1CTSDNAALAD2GNPATMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |