Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366744 | 0.97 | NAALAD2 (0.55) | BACE1NAALAD2CTSDPTPN1GNPAT | |
| SCHEMBL29630505 | 0.93 | BACE1 (0.58) | BACE1NAALAD2CTSDGNPATBACE2 | |
| SCHEMBL29590787 | 0.92 | BACE1 (0.60) | BACE1NAALAD2CTSDGNPATBACE2 | |
| SCHEMBL30567796 | 0.92 | BACE1 (0.56) | BACE1NAALAD2CTSDPTPN1BACE2 | |
| SCHEMBL31482978 | 0.92 | BACE1 (0.52) | BACE1NAALAD2CTSDGNPAT | |
| SCHEMBL29630438 | 0.92 | BACE1 (0.52) | BACE1NAALAD2CTSDGNPAT | |
| SCHEMBL30483779 | 0.92 | NAALAD2 (0.64) | BACE1NAALAD2CTSDPTPN1GNPAT | |
| SCHEMBL30799809 | 0.91 | PTPN1 (0.60) | BACE1CTSDPTPN1BACE2 | |
| SCHEMBL30903437 | 0.90 | BACE1 (0.51) | BACE1NAALAD2CTSDGNPAT | |
| SCHEMBL30460370 | 0.90 | BACE1 (0.60) | BACE1NAALAD2CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |