SCHEMBL29630696

SCHEMBL29630696

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nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.57
BACE1 P56817 6/20 0.48
DPP4 P27487 2/20 0.41
DPP8 Q6V1X1 2/20 0.41
DPP9 Q86TI2 2/20 0.41
DPP7 Q9UHL4 2/20 0.41
FAP Q12884 1/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
ITGB2 P05107 1/20 0.38
ICAM1 P05362 1/20 0.38
ITGAL P20701 1/20 0.38
SLC7A5 Q01650 1/20 0.38
CTSD P07339 1/20 0.38
CA2 P00918 1/20 0.37
ALDH1A1 P00352 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28182230 0.94 ECE1 (0.64) ECE1BACE1DPP4DPP8DPP9
SCHEMBL28182232 0.94 ECE1 (0.64) ECE1BACE1DPP4DPP8DPP9
SCHEMBL11050000 0.91 BACE1 (0.54) ECE1BACE1CTSD
SCHEMBL11049992 0.89 BACE1 (0.60) ECE1BACE1CTSD
SCHEMBL29630757 0.89 ECE1 (0.52) ECE1BACE1PDCD1LG2CD274ITGB2
SCHEMBL29630570 0.89 ECE1 (0.52) ECE1BACE1PDCD1LG2CD274ITGB2
SCHEMBL29434587 0.89 ECE1 (0.52) ECE1BACE1PDCD1LG2CD274ITGB2
SCHEMBL29630705 0.89 ECE1 (0.52) ECE1BACE1PDCD1LG2CD274ITGB2
SCHEMBL7241324 0.89 ECE1 (0.44) ECE1BACE1DPP4DPP8DPP9
SCHEMBL7241330 0.89 ECE1 (0.44) ECE1BACE1DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230414771-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY CONJUGATED COMPLEXES FOR TARGETED DELIVERY AND ACTIVATION YAFEI SHANGHAI BIOLOGY MEDICINE SCIENCE & TECHNOLOGY CO., LTD. (CN) 2023-12-28 US claimed
EP-4108675-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) 2022-12-28 EP claimed
US-11319341-B2 Immune-stimulating soluble doxorubicin-conjugated complex YAFEI (SHANGHAI) BIOPHARMACEUTICAL CO., LTD. (CN) 2022-05-03 US claimed
CN-113274507-B Preparation and use of targeted delivery and activation immunostimulatory conjugate complexes 亚飞(上海)生物医药科技有限公司 2025-02-28 CN disclosed
US-20230414771-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY CONJUGATED COMPLEXES FOR TARGETED DELIVERY AND ACTIVATION YAFEI SHANGHAI BIOLOGY MEDICINE SCIENCE & TECHNOLOGY CO., LTD. (CN) 2023-12-28 US disclosed
US-11718839-B1 Compositions and methods for deactivating enveloped viruses such as SARS-CoV-2 ILLINOIS INSTITUTE OF TECHNOLOGY (US) 2023-08-08 US disclosed
EP-4108675-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) 2022-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319341-B2 Immune-stimulating soluble doxorubicin-conjugated complex TLR3, CD40, TLR6 ECE1 1561/4885BACE1 2608/4885DPP4 4632/4885
US-20230414771-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY CONJUGATED COMPLEXES FOR TARGETED DELIVERY AND ACTIVATION CD74, PAICS, MIF ECE1 3284/4885BACE1 3856/4885DPP4 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.