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Sugi Predict / Compounds / SCHEMBL29630727

SCHEMBL29630727

SCHEMBL29630727

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nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 12/20 0.54
▸ CTSD P07339 3/20 0.54
▸ OPRD1 P41143 2/20 0.46
▸ ENPEP Q07075 5/20 0.44
▸ BACE2 Q9Y5Z0 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374714 0.93 BACE1 (0.48) BACE1CTSDOPRD1ENPEP
SCHEMBL30797948 0.91 GNPAT (0.46) BACE1CTSDENPEP
SCHEMBL30799433 0.89 BACE1 (0.50) BACE1CTSDOPRD1ENPEPBACE2
SCHEMBL29873713 0.88 ENPEP (0.50) BACE1ENPEP
SCHEMBL30408803 0.88 PTPN1 (0.45) BACE1CTSDOPRD1ENPEP
SCHEMBL30799921 0.88 PTPN1 (0.45) BACE1CTSDOPRD1ENPEP
SCHEMBL31181173 0.88 ENPEP (0.44) BACE1CTSDOPRD1ENPEPBACE2
SCHEMBL29591595 0.87 BACE1 (0.52) BACE1CTSDOPRD1ENPEPBACE2
SCHEMBL31162635 0.86 GNPAT (0.51) BACE1CTSDOPRD1ENPEPBACE2
SCHEMBL31089740 0.85 ENPEP (0.55) BACE1CTSDENPEPBACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 — — US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 — — US disclosed