SCHEMBL29630745

SCHEMBL29630745

NC(=O)CC[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 2/20 0.43
PTGS1 P23219 1/20 0.42
GSTK1 Q9Y2Q3 1/20 0.42
PDCD1LG2 Q9BQ51 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
BMP1 P13497 1/20 0.40
EGFR P00533 1/20 0.38
BACE1 P56817 3/20 0.36
CTSD P07339 1/20 0.36
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
ALOX15 P16050 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30099639 0.97 GLO1 (0.41) GLO1PTGS1GSTK1PDCD1LG2CD274
SCHEMBL29682736 0.96 GLO1 (0.44) GLO1PTGS1GSTK1PDCD1LG2CD274
SCHEMBL30069089 0.95 GLO1 (0.44) GLO1PTGS1GSTK1PDCD1LG2CD274
SCHEMBL30612515 0.91 PDCD1LG2 (0.47) GLO1PTGS1GSTK1PDCD1LG2CD274
SCHEMBL29644351 0.89 PDCD1LG2 (0.44) GLO1PTGS1GSTK1PDCD1LG2CD274
SCHEMBL29744873 0.89 PDCD1LG2 (0.44) GLO1PTGS1GSTK1PDCD1LG2CD274
SCHEMBL29693286 0.88 GLO1 (0.49) GLO1PTGS1GSTK1BMP1EGFR
SCHEMBL30974035 0.87 GLO1 (0.46) GLO1PTGS1GSTK1BMP1EGFR
SCHEMBL7575589 0.86 GLO1 (0.44) GLO1PTGS1GSTK1BMP1EGFR
SCHEMBL30903459 0.85 GLO1 (0.50) GLO1PTGS1GSTK1BMP1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed