Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.58 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 11/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893699 | 1.00 | TTBK1 (0.58) | TTBK1TTBK2KDRPDGFRAMET | |
| SCHEMBL4364193 | 0.83 | MET (0.45) | TTBK1TTBK2KDRMETBRAF | |
| SCHEMBL1895723 | 0.82 | PDGFRA (0.47) | TTBK1TTBK2KDRPDGFRAHSPB1 | |
| SCHEMBL30844464 | 0.81 | KMT2A (0.52) | TTBK1TTBK2MET | |
| SCHEMBL4249568 | 0.81 | MET (0.55) | METHSPB1 | |
| SCHEMBL29631514 | 0.81 | MET (0.55) | METHSPB1 | |
| SCHEMBL3484554 | 0.81 | KMT2A (0.52) | TTBK1TTBK2MET | |
| SCHEMBL4361630 | 0.80 | MET (0.45) | TTBK1TTBK2KDRMETBRAF | |
| SCHEMBL30310261 | 0.80 | PDGFRA (0.47) | TTBK1TTBK2KDRPDGFRAHSPB1 | |
| SCHEMBL26084095 | 0.80 | PDGFRA (0.47) | TTBK1TTBK2KDRPDGFRAHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520416-B | Polysubstituted pyridone derivative, preparation method and medical application thereof | 北京越之康泰生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |