Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.59 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29632741 | 0.83 | MAPK1 (0.46) | CTSKPIM1PIM2 | |
| SCHEMBL29632662 | 0.83 | CTSK (0.42) | CTSKNUDT1MAP4K4HRH4SMN1; SMN2 | |
| SCHEMBL12290871 | 0.83 | CCNT1 (0.45) | CTSKNUDT1PIM1PIM3PIM2 | |
| SCHEMBL12293060 | 0.83 | CCNT1 (0.45) | CTSKNUDT1PIM1PIM3PIM2 | |
| SCHEMBL29682770 | 0.81 | IRAK4 (0.53) | HRH4PIM1PIM2 | |
| SCHEMBL29682485 | 0.81 | IRAK4 (0.53) | HRH4PIM1PIM2 | |
| SCHEMBL1196889 | 0.80 | HRH4 (0.50) | CTSKHRH4PIM1 | |
| Hydrochloric Acid SCHEMBL3113787 | 0.79 | HRH4 (0.49) | CTSKHRH4PIM1 | |
| SCHEMBL29632728 | 0.79 | CTSK (0.59) | CTSKNUDT1MAP4K4KDM4EGAA | |
| SCHEMBL18284684 | 0.77 | MKNK1 (0.39) | CTSKPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086284-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2022-04-28 | — | — | WO | disclosed |