Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936302 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL29788605 | 0.77 | MEN1 (0.47) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL28548601 | 0.77 | MEN1 (0.47) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL24936306 | 0.71 | MAPT (0.35) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL29045194 | 0.70 | CYP1A2 (0.35) | KDM4EGAASMN1; SMN2CYP1A2CYP19A1 | |
| SCHEMBL29632631 | 0.67 | CYP1A2 (0.52) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL23084830 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL8244559 | 0.66 | IKBKB (0.44) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL18955276 | 0.66 | CYP1A2 (0.43) | KDM4EALDH1A1GAACYP1A2CYP19A1 | |
| SCHEMBL2093729 | 0.66 | CYP1A2 (0.62) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403571-A | Therapeutic agent for cancer having therapeutic resistance to immune checkpoint inhibitor | 住友制药株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-116546974-A | 5-heteroaryl-1H-pyrazol-3-amine derivatives | 住友制药株式会社 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022114189-A1 | 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE | 住友ファーマ株式会社 | 2022-06-02 | — | — | WO | disclosed |