Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859444 | 0.77 | ACHE (0.59) | ACHEHRH3ALDH1A1HTR7RAB9A | |
| SCHEMBL17108785 | 0.76 | ACHE (0.50) | ACHEHRH3ALDH1A1HTR7RAB9A | |
| SCHEMBL18908952 | 0.75 | ACHE (0.62) | ACHEHRH3ALDH1A1HTR7RAB9A | |
| SCHEMBL5345098 | 0.72 | ACHE (0.50) | ACHEHRH3ALDH1A1HTR7RAB9A | |
| SCHEMBL15014582 | 0.71 | ACHE (0.58) | ACHEHRH3ALDH1A1HTR7KDM4E | |
| SCHEMBL4246188 | 0.71 | ACHE (0.68) | ACHEHRH3ALDH1A1KDM4EKMT2A | |
| SCHEMBL17828173 | 0.71 | ACHE (0.45) | ACHEHRH3ALDH1A1HTR7KMT2A | |
| SCHEMBL156315 | 0.71 | ACHE (1.00) | ACHEHRH3ALDH1A1HTR7 | |
| SCHEMBL15214316 | 0.70 | ACHE (0.56) | ACHEHRH3ALDH1A1HTR7PARP1 | |
| SCHEMBL13499607 | 0.70 | ACHE (1.00) | ACHEHRH3HTR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086284-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2022-04-28 | — | — | WO | disclosed |