Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665894 | 1.00 | PPARA (0.57) | PPARABCHEFOLH1PPARGPTGER4 | |
| SCHEMBL29633035 | 0.89 | PPARA (0.54) | PPARABCHEFOLH1PPARGPTGER4 | |
| SCHEMBL28684375 | 0.89 | PPARA (0.54) | PPARABCHEFOLH1PPARGPTGER4 | |
| SCHEMBL29632995 | 0.87 | PPARA (0.54) | PPARABCHEFOLH1PPARGPTGER4 | |
| SCHEMBL28665892 | 0.87 | PPARA (0.54) | PPARABCHEFOLH1PPARGPTGER4 | |
| SCHEMBL29633009 | 0.82 | BID (0.59) | PPARAPPARGALOX5PTGS2BID | |
| SCHEMBL28665897 | 0.82 | PPARA (0.58) | PPARABCHEFOLH1PPARGPTGER4 | |
| SCHEMBL28474342 | 0.81 | FOLH1 (0.70) | PPARAFOLH1PPARGPTGER4PTGER3 | |
| SCHEMBL4294270 | 0.78 | PPARA (0.78) | PPARAPPARGALOX5PTGS2BID | |
| SCHEMBL31220510 | 0.75 | BID (0.59) | PPARAPPARGALOX5PTGS2BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275711-B2 | Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2025-04-15 | — | — | US | disclosed |
| CN-113692403-B | Compounds having excited state intramolecular proton transfer (esit) properties for use in the treatment and/or prevention of sunburn and/or prevention of u.v. damage | 约翰内斯堡威特沃特斯兰德大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20220144785-A1 | COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275711-B2 | Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage | NNT, NQO1, SUN2 | PPARA 3232/4885BCHE 348/4885FOLH1 2039/4885 |
| US-20220144785-A1 | COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE | NNT, NQO1, SUN2 | PPARA 3232/4885BCHE 348/4885FOLH1 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.