Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | BID | P55957 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665892 | 1.00 | PPARA (0.54) | PPARAFOLH1PPARGBIDMCL1 | |
| SCHEMBL29633018 | 0.87 | PPARA (0.57) | PPARAFOLH1PPARGBIDMCL1 | |
| SCHEMBL28665894 | 0.87 | PPARA (0.57) | PPARAFOLH1PPARGBIDMCL1 | |
| SCHEMBL28474342 | 0.87 | FOLH1 (0.70) | PPARAFOLH1PPARGBIDMCL1 | |
| SCHEMBL28665897 | 0.85 | PPARA (0.58) | PPARAFOLH1PPARGBIDMCL1 | |
| SCHEMBL29633035 | 0.85 | PPARA (0.54) | PPARAFOLH1PPARGBCHEPTGER4 | |
| SCHEMBL28684375 | 0.85 | PPARA (0.54) | PPARAFOLH1PPARGBCHEPTGER4 | |
| SCHEMBL10956404 | 0.79 | HTR1A (0.65) | THRATHRBBCHEPTGER1PTGER4 | |
| SCHEMBL28375679 | 0.79 | HTR1A (0.65) | THRATHRBBCHEPTGER1PTGER4 | |
| SCHEMBL28476408 | 0.77 | ALOX5 (0.64) | PPARAFOLH1PPARGBCHEPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275711-B2 | Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2025-04-15 | — | — | US | disclosed |
| CN-113692403-B | Compounds having excited state intramolecular proton transfer (esit) properties for use in the treatment and/or prevention of sunburn and/or prevention of u.v. damage | 约翰内斯堡威特沃特斯兰德大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20220144785-A1 | COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275711-B2 | Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage | NNT, NQO1, SUN2 | PPARA 3232/4885FOLH1 2039/4885PPARG 3226/4885 |
| US-20220144785-A1 | COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE | NNT, NQO1, SUN2 | PPARA 3232/4885FOLH1 2039/4885PPARG 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.