Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22120114 | 1.00 | KCNH2 (0.48) | KCNH2HRH1HRH4CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL10372072 | 0.86 | KCNH2 (0.51) | KCNH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22073049 | 0.84 | GRIN2D (0.44) | KCNH2HRH4GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL9153717 | 0.82 | GRIN2D (0.46) | KCNH2HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28693450 | 0.81 | KCNH2 (0.48) | KCNH2CYP4F2CYP4A11 | |
| SCHEMBL15102639 | 0.81 | GRIN2D (0.44) | KCNH2HRH4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14732900 | 0.80 | CCR1 (0.44) | KCNH2 | |
| Hydrochloric Acid SCHEMBL17984763 | 0.79 | GRIN2D (0.46) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16579386 | 0.79 | HRH4 (0.37) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17866588 | 0.77 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388542-A1 | ANALOGUES OF PENTAMIDINE AND USES THEREFOR | AURANSA INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-20220144776-A1 | ANALOGUES OF PENTAMIDINE AND USES THEREFOR | AURANSA INC. | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388542-A1 | ANALOGUES OF PENTAMIDINE AND USES THEREFOR | MALT1, SLC38A7, SLC7A1 | KCNH2 4100/4885HRH1 112/4885HRH4 244/4885 |
| US-20220144776-A1 | ANALOGUES OF PENTAMIDINE AND USES THEREFOR | DPYD, TYMP, GOT1 | KCNH2 4581/4885HRH1 1437/4885HRH4 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.