Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | UBE2I | P63279 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22972185 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL22972399 | 0.92 | HPGD (0.52) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL22972362 | 0.90 | HPGD (0.66) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL22972401 | 0.85 | HPGD (0.54) | ALDH1A1KDM4EHPGDGAAHTT | |
| SCHEMBL22972240 | 0.84 | HPGD (0.57) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL22972410 | 0.84 | GAA (0.52) | HPGDGAA | |
| SCHEMBL22972235 | 0.83 | MAPT (0.55) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL30049303 | 0.83 | DDR2 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29318681 | 0.83 | DDR2 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL24724231 | 0.83 | KDR (0.54) | HPGDGAADDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010330-A1 | QUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. Pharma (BE) | 2022-06-15 | — | — | EP | disclosed |