Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 1.00 |
| ▸ | HTT | P42858 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | ATM | Q13315 | 4/20 | 1.00 |
| ▸ | MITF | O75030 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | XBP1 | P17861 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.73 |
| ▸ | CDC25A | P30304 | 5/20 | 0.73 |
| ▸ | CDC25B | P30305 | 3/20 | 0.73 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.73 |
| ▸ | HK1 | P19367 | 1/20 | 0.73 |
| ▸ | CDC25C | P30307 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506683 | 1.00 | MAPT (1.00) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL32664539 | 0.89 | MAPT (0.79) | MAPTHTTRAB9AKMT2ANPSR1 | |
| Dichlon SCHEMBL6439548 | 0.88 | MAPT (0.78) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL4868219 | 0.85 | MAPT (1.00) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL7240445 | 0.85 | MAPT (0.74) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL4873496 | 0.85 | MAPT (1.00) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL8663288 | 0.85 | MAPT (0.74) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL7912341 | 0.85 | MAPT (0.73) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL12283357 | 0.85 | MAPT (0.73) | MAPTHTTRAB9AKMT2ANPSR1 | |
| SCHEMBL2241314 | 0.84 | KMT2A (0.71) | MAPTHTTRAB9AKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748809-B | Method for synthesizing 2-substituted amino-1, 4-naphthoquinone derivative | 中国科学院成都有机化学有限公司 | 2022-05-13 | — | — | CN | disclosed |