Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633542 | 0.85 | TSHR (0.46) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL22533321 | 0.83 | TSHR (0.44) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL29633557 | 0.83 | TSHR (0.44) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL31171420 | 0.76 | TSHR (0.60) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL31171418 | 0.76 | TSHR (0.60) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL28060602 | 0.75 | KDM4E (0.49) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL3997791 | 0.74 | TSHR (0.58) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL17893920 | 0.74 | TSHR (0.42) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E | |
| SCHEMBL289285 | 0.73 | CA12 (0.55) | TSHRHSD17B10ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL28639005 | 0.73 | TSHR (0.45) | TSHRHSD17B10ALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |