SCHEMBL29633563

SCHEMBL29633563

OCC#Cc1ccccc1F

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MME P08473 7/20 0.43
ECE1 P42892 7/20 0.43
HCAR2 Q8TDS4 1/20 0.40
GRM5 P41594 3/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
TRPV3 Q8NET8 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
IKBKB O14920 1/20 0.34
PAX8 Q06710 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2163949 1.00 MME (0.43) MMEECE1HCAR2GRM5ALDH1A1
SCHEMBL10694244 0.84 ALDH1A1 (0.37) MMEECE1HCAR2ALDH1A1KDM4E
SCHEMBL6449051 0.84 CYP1A2 (0.44) ALDH1A1KDM4ECYP1A2CYP3A4MAPT
SCHEMBL30515632 0.84 CYP1A2 (0.44) ALDH1A1KDM4ECYP1A2CYP3A4MAPT
SCHEMBL2953233 0.83 KDM4E (0.47) MMEECE1HCAR2GRM5ALDH1A1
SCHEMBL15022608 0.80 KDM4E (0.57) MMEECE1HCAR2GRM5ALDH1A1
SCHEMBL23122854 0.78 CYP2C19 (0.50) MMEECE1HCAR2GRM5CYP1A2
SCHEMBL5392887 0.78 MME (0.40) MMEECE1HCAR2GRM5PTGDR2
SCHEMBL436732 0.78 MME (0.40) MMEECE1HCAR2GRM5PTGDR2
SCHEMBL17771436 0.78 GRM5 (0.42) MMEECE1HCAR2GRM5PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466790-B Preparation method of alpha-sulfinylated carbonyl compound 西北师范大学 2024-05-28 CN claimed
CN-117466790-A Preparation method of alpha-sulfinylated carbonyl compound 西北师范大学 2024-01-30 CN claimed
CN-119823001-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-15 CN disclosed
CN-114206832-B Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2025-04-04 CN disclosed
CN-111285874-B RET inhibitor, pharmaceutical composition thereof and application thereof 广东东阳光药业股份有限公司 2024-08-09 CN disclosed
CN-117466790-B Preparation method of alpha-sulfinylated carbonyl compound 西北师范大学 2024-05-28 CN disclosed
CN-117466790-A Preparation method of alpha-sulfinylated carbonyl compound 西北师范大学 2024-01-30 CN disclosed
CN-114206832-A Urea compounds antagonizing LPA1 receptor 大正制药株式会社 2022-03-18 CN disclosed