Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338863 | 1.00 | IDO1 (0.53) | IDO1CYP19A1MAPTGBA1ADRA2A | |
| SCHEMBL10530881 | 0.86 | IDO1 (0.50) | IDO1CYP19A1MAPTGBA1ADRA2A | |
| SCHEMBL9567953 | 0.86 | GBA1 (0.55) | IDO1CYP19A1GBA1SIGMAR1 | |
| SCHEMBL10957708 | 0.81 | SIGMAR1 (0.50) | IDO1CYP19A1SIGMAR1HTR2A | |
| SCHEMBL835059 | 0.80 | IDO1 (0.47) | IDO1CYP19A1MAPTGBA1ADRA2A | |
| SCHEMBL29447948 | 0.80 | IDO1 (0.47) | IDO1CYP19A1MAPTGBA1ADRA2A | |
| SCHEMBL22868015 | 0.77 | SLC6A2 (0.39) | IDO1SIGMAR1 | |
| SCHEMBL9692838 | 0.77 | SIGMAR1 (0.50) | SIGMAR1HTR2A | |
| SCHEMBL30046780 | 0.77 | CYP19A1 (0.38) | IDO1CYP19A1ADRA2ADRD3 | |
| SCHEMBL9245611 | 0.77 | CYP19A1 (0.38) | IDO1CYP19A1ADRA2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |