Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20763257 | 0.95 | KMT2A (0.54) | KDM4ECREBBPALDH1A1KMT2ATSHR | |
| SCHEMBL25980683 | 0.89 | USP2 (0.50) | KDM4ECREBBPALDH1A1KMT2ATSHR | |
| SCHEMBL25980852 | 0.89 | LMNA (0.52) | KDM4ECREBBPALDH1A1KMT2ATSHR | |
| SCHEMBL29633615 | 0.87 | KDM4E (0.44) | KDM4ECREBBPALDH1A1KMT2ATSHR | |
| SCHEMBL3635413 | 0.87 | CA12 (0.58) | ALDH1A1KMT2ATSHRCA12CA1 | |
| SCHEMBL29633564 | 0.86 | KDM4E (0.43) | KDM4ECREBBPALDH1A1KMT2ATSHR | |
| SCHEMBL28030473 | 0.85 | TSHR (0.66) | ALDH1A1KMT2ATSHRMEN1LMNA | |
| SCHEMBL6865895 | 0.84 | CREBBP (0.49) | KDM4ECREBBPALDH1A1KMT2ATSHR | |
| SCHEMBL18018670 | 0.84 | EGFR (0.48) | KDM4EALDH1A1KMT2ATSHRCA12 | |
| SCHEMBL3576601 | 0.84 | LMNA (0.57) | KDM4ECREBBPALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |