Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043058 | 0.82 | CA1 (0.44) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL321818 | 0.81 | CA1 (0.47) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL17892935 | 0.77 | CA1 (0.40) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL11083912 | 0.77 | THRB (0.48) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL27820091 | 0.76 | AKR1C4 (0.42) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL843194 | 0.74 | AKR1C2 (0.54) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL15864848 | 0.73 | CA1 (0.53) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL842678 | 0.73 | CA1 (0.44) | AKR1C2AKR1C1CA1CA2AKR1C4 | |
| SCHEMBL2456581 | 0.72 | CSNK2A1 (0.47) | CA1CA2CSNK2A1HPGDHSD17B10 | |
| SCHEMBL39512 | 0.72 | CSNK2A1 (0.47) | CA1CA2CSNK2A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |