Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802981 | 0.88 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL1298246 | 0.84 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL6736374 | 0.84 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL23440383 | 0.83 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL2345801 | 0.83 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL2341343 | 0.83 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL2341968 | 0.83 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL2341347 | 0.83 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL30730195 | 0.83 | CHRNB2 (0.47) | ALDH1A1 | |
| SCHEMBL25228915 | 0.83 | KMT2A (0.44) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |